This practice point considers azithromycin therapy for acute respiratory infections in otherwise healthy children
Harris and colleagues49 reported the results from a multicenter study of children with community-acquired pneumonia
The median trough level was
As a second-generation macrolide antibiotic, azithromycin is widely used in the treatment of various infectious diseases, and its pediatric clinical application rate
To assess whether adding oral azithromycin to standard asthma therapy in children with poorly controlled asthma improves asthma control
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Azithromycin is an acid-stable orally administered macrolide antimicrobial drug, structurally related to erythromycin []
The median dosage of azithromycin was 10 mg/kg/day in the enrolled patients
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Among these
This insufficient knowledge of the appropriate clinical indications for antibiotic prescriptions promotes the overuse of antibiotics and contributes to the 7–14 Subjects reported that it took a mean of 16 ± 12 days (median, 9 days; range, 2 to 45 days) before they began to improve symptomatically after initiating azithromycin therapy
Yuhong Guan, Xiang Zhang, placebo-controlled trial showed azithromycin maintenance therapy for 6 months was well tolerated and halved the rate of respiratory (range 0
Objectives To determine whether administration of azithromycin (AZM) to children with RSV-induced respiratory failure is safe and to define the effect of AZM therapy on nasal matrix metalloproteinase 9 (MMP-9) levels
In adults given 500 mg/day for 3 days, the discontinuation rate due to treatment-related adverse reactions was 0
Travelers’ diarrhea (TD) is the most predictable travel-related illness
Azithromycin is an antibiotic that is commonly prescribed for upper and lower respiratory tract infections in children
Treatment with antibacterial (azithromycin) therapy because of treatment-related adverse reactions
In CHEST (June 2022), Ghimire and colleagues
azithromycin therapy emphasizing that the drug should be AZITHROMYCIN PHARMACOKINETICS IN PEDIATRIC PATIENTS 315 linear range extended from 10 to 250 ng/ml
Dosing recommendations are based on estimated GFR using the modified Schwartz equation1, which has not been validated in children <1 year of age
Azithromycin (Zithromax®) mg/mL X Dilute to 2 Infusion:MAX concentration of 2 mg/mL over 1 hr Dosing: 5-10 mg/kg/day as q 24 h (MAX 500 mg) Single dose regimen: 30mg/kg X 1 (MAX 1500mg) For specific indications, please consult pedi reference for recommendations
4 Pediatric Use