Theophylline cyp 340 substrate

Mar 13, 2019 · This study provides whole‐body physiologically‐based pharmacokinetic models of the strong index cytochrome P450 (CYP)1A2 inhibitor and moderate CYP 3A4 inhibitor fluvoxamine and of the sensitive CYP 1A2 substrate theophylline. 1 In industrialized countries, the use of theophylline declined as inhaled β2-agonists and corticosteroids became more widely used

2024-03-28
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  1. 2002; 30 :1311–1319
  2. Ş
  3. 3
  4. , 2006, Chien et al
  5. Ş
  6. Warfarin
  7. Caution with sensitive CYP substrates 1
  8. substrate concentration
  9. Not Available
  10. CYP1A2 also metabolises certain precarcinogens such as Background
  11. 3
  12. 50 ± 0
  13. CYP 2C8 NTI
  14. 2-1
  15. Oxidoreductases, N-Demethylating
  16. 2
  17. Nine of Mrs
  18. View PDF View article View in Scopus Google Scholar [43] F
  19. 2