Clopidogrel is a prodrug that is absorbed in the intestine [3,4] and activated in the liver
Clopidogrel inhibits platelet activation and aggregation by the irreversible binding of its active metabolite (GPIIb/IIIa) to platelet P2Y12 adenosine diphosphate (ADP) receptors
Clopidogrel is activated via a 2 steps reaction to an active thiol-containing metabolite
It reduces the chance that a harmful blood clot will form by preventing platelets from clumping together in the blood
Clopidogrel is active only after
Because this
1 INTRODUCTION
Mechanism of action Clopidogrel acts by inhibiting ADP induced platelet aggregation