Linezolid belongs to a new class of antibiotics known as oxazolidinones
Brand names Why is this medication prescribed? Linezolid is used to treat infections, including pneumonia, and infections of the skin
Generic name: linezolid (oral/injection) [ lin-EZ-oh-lid ] Brand name: Zyvox Dosage forms: intravenous solution (2 mg/mL-D5%; 2 mg/mL-NaCl 0
[3] Medical uses Linezolid is a synthetic oxazolidinone with bacteriostatic activity against gram-positive organisms [ 1 ]
Star 1 Summary Linezolid is an oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria
Linezolid (Zyvox) is a synthetic antibiotic that is effective against bacteria such as Enterococcus faecium, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus
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During the last 40 years, oxazolidinones have been considered a truly new class of antibiotics which are currently used in clinics
It is indicated for gram-positive infections and approved for the treatment of bacterial pneumonia, skin and skin structure infections, and VRE infections, including infections complicated by bacteremia
CAS number: 165800-03-3
If this occurs, there are certain precautions your doctor may ask you to take, especially when Cox 2012 and Sotgiu 2012 concluded that linezolid was efficacious for drug‐resistant tuberculosis, though both advised caution in its use due to high incidence of adverse events
Generic Zyvox
It works by killing bacteria or preventing their growth
163 major drug interactions (768 brand and generic names); 349 moderate drug interactions (1433 brand and generic names); 2 minor drug interactions (3 brand and generic names); A total of 159 drugs are known to interact with
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Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice
On Days 2–9, subjects were given either Vitamin C (1000 mg/day) or Vitamin E (800 IU/
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, myelosuppression, peripheral neuropathy, and optic neuritis), and to achieve a peak serum linezolid level of 12–26
The most common side effects leading to discontinuation were diarrhea, headache, nausea, and vomiting
Dose: 20 mg/kg/day PO/IV divided q12h x14-28 days; Info: incr