Checklist: Contact transplant PharmD (Appendix B) to evaluate for all drug-drug interactions in table above and Liverpool reference
These agents
Paxlovid is an antiviral therapy that consists of two separate medications packaged together
The 2 medicines are taken
There are 659 drugs known to interact with Paxlovid (nirmatrelvir/ritonavir), along with 7 disease interactions, and 2 alcohol/food interactions
Key Points Paxlovid (nirmatrelvir and ritonavir) is an oral antiviral medicine used to treat mild-to-moderate COVID-19
dilTIAZem ritonavir
Blood pressure increase (hypertension) High blood pressure was listed as a side effect with Paxlovid, but it’s not very common
NDC 62332-027-91 bottles of 1000 tablets
Eplerenone works similarly to losartan, but its levels increase when taken with grapefruit
Common interactions include pain among females, and dizziness among males
As a result, losartan relaxes the blood vessels
If you are taking irbesartan you should avoid potassium-containing salt substitutes or over-the-counter potassium supplements without first talking to your doctor
Losartan may cause serious side effects
Before prescribing ritonavir-boosted nirmatrelvir to treat patients with mild to moderate COVID-19, carefully review the patient’s concomitant medications, including over-the-counter medicines, herbal Who can take Paxlovid
you've had COVID-19 symptoms within the last 5 days
As with any medication, there may be side effects that occur when taking Paxlovid
86), Table 2 presents more details
6
These medications are also referred to as water pills
Applies to: carvedilol and Paxlovid (nirmatrelvir / ritonavir) Ritonavir may increase the blood levels and effects of carvedilol