GoodRx Health If you have mild to moderate COVID-19, you may be eligible to receive a prescription for Paxlovid (nirmatrelvir/ritonavir)
You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications
Additional resources include NIH recommendations for drug-drug interactions between PAXLOVID and UpToDate PAXLOVID drug information
Additional information available in Fact Sheet for Healthcare Providers or Liverpool COVID-19 Drug Interaction site
Management of Drug Interactions With Nirmatrelvir/Ritonavir (Paxlovid®): Resource for Clinicians Facebook Twitter LinkedIn Email
1 It has demonstrated antiviral activity against all coronaviruses that are known to infect humans
Adjust dosing based on therapeutic drug level monitoring as indicated
A review paper published today in the Journal of the American College of Cardiology examines the potential drug-drug Home Medicines A to Z Paxlovid Taking Paxlovid with other medicines and herbal supplements If you are taking ritonavir as part of your treatment for HIV or hepatitis C infection, you can continue taking your treatment as usual
This is when a medication reacts with one or more other drugs
22, 2024 -- The risk of being hospitalized because of COVID-19 was reduced by 84% among people who used Paxlovid, reports a new study
You should avoid or limit the use of alcohol while being treated with cetirizine
The relevance of a particular drug interaction to a specific individual is difficult to determine
Tell your doctor about all other medicines you use
The phase IV clinical study analyzes what interactions people who take Allegra and Paxil have
These classifications are only a guideline
Moderate Applies to: Paxlovid (nirmatrelvir / ritonavir) and Eliquis (apixaban) Ritonavir may significantly increase the blood levels of apixaban
The U
If you take hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding
metoprolol ritonavir
The relevance of a particular drug interaction to a specific individual is difficult to determine
Talk to your doctor before using sildenafil together with ritonavir
Let your doctor know if your condition changes or you experience increased side effects of DULoxetine such as The list of interactions with Paxlovid is long
com These classifications are only a guideline
Moderate Applies to: Paxlovid (nirmatrelvir / ritonavir) and Xarelto (rivaroxaban) Ritonavir may significantly increase the blood levels of rivaroxaban
You should avoid activities requiring mental alertness until you know how these medications affect you
The relevance of a particular drug interaction to a specific individual is difficult to determine
The relevance of a particular drug interaction to a specific individual is difficult to determine
Ritonavir may interfere with blood glucose control and reduce the effectiveness of alogliptin and other diabetic medications
Always consult your healthcare provider before starting or stopping any medication
This may increase side effects such as nausea, vomiting, diarrhea, abdominal pain, hemorrhage, development of other cancers, abnormal heart rhythm, and impaired bone propranolol ritonavir
You may be more likely to experience side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual Drug-Drug Interactions with Nirmatrelvir/Ritonavir (Paxlovid) and Select Cardiovascular Medications NOTE: Holding or reducing the dose of select cardiovascular medications and/or other special monitoring requirements are recommended during treatment with nirmaltrelvir/ritonavir (Paxlovid) and for 3 days thereafter (for a total of 8 days from the Risk of adverse drug interactions with Paxlovid
Combining these medications may significantly increase the blood levels and effects of alfuzosin
Do not use more than the recommended dose Applies to: pravastatin and Paxlovid (nirmatrelvir / ritonavir) Using ritonavir together with pravastatin may decrease the effects of pravastatin
Monitor your blood sugar levels closely
Combining these medications may increase the absorption of fluticasone nasal into the blood stream
ritonavir tenofovir
In a clinical trial, ritonavir-boosted nirmatrelvir reduced the risk of hospitalization and death by 86% in unvaccinated outpatients with COVID-19 at higher risk of severe disease
Do not change your treatment or stop treatment without first talking to your doctor
They can check if methylprednisolone interacts with any of your medications
Avoid combinations; the risk of the interaction outweighs the benefit
Here's what
Checklist: Contact transplant PharmD (Appendix B) to evaluate for all drug-drug interactions in table above and Liverpool reference
Of note, this is not a comprehensive table, but
Everolimus ↑ Everolimus levels and
Five of the most important cardiovascular drug interactions with Paxlovid to be aware of include: Antiarrhythmic agents
The main types are: Drug-drug interaction
The European Medicines Agency (EMA) has issued a warning regarding a potentially life-threatening interaction that could occur when taking the COVID drug Paxlovid along
Many of these drugs are metabolized in a way that increases plasma levels when co-administered with Paxlovid
Major: Highly clinically significant
Pharmacists can be a valuable resource for assessing and helping manage these interactions
Always consult your healthcare provider before starting or stopping any medication
Talk to your doctor if you have any questions or concerns
Paxlovid (EUA) 300 Mg (150 X 2)-100 Tablet Pharmacoenhancer - Cytochrome P450 Inhibitors - Uses, Side Effects, and More Generic Name(S): nirmatrelvir-ritonavir The table below provides recommendations for management of drug-drug interactions for patients being prescribed Paxlovid
Always consult your healthcare provider before starting or stopping any medication
Always consult your healthcare provider before starting or stopping any medication
This may increase side effects such as nausea, vomiting, diarrhea, abdominal pain, hemorrhage, development of other cancers, abnormal heart rhythm, and impaired bone propranolol ritonavir
Risk of adverse drug interactions with Paxlovid
Combining these medications may significantly increase the blood levels and effects of alfuzosin
Do not use more than the recommended dose Applies to: pravastatin and Paxlovid (nirmatrelvir / ritonavir) Using ritonavir together with pravastatin may decrease the effects of pravastatin
Monitor your blood sugar levels closely
Applies to: Paxlovid (nirmatrelvir / ritonavir) and azelastine / fluticasone nasal
You may need a dose adjustment if you have been taking codeine and are starting treatment with ritonavir