Therefore, it is clear that rosuvastatin, and other statins, are very safe and useful
Tubular toxicity should be considered in cases of
Reserve higher initial dose for patients with severe hypercholesteremia or patients with homozygous familial hypercholesterolemia
6 for hematuria, 3
Inform patients of the risk of myopathy and rhabdomyolysis when starting or increasing CRESTOR dosage
However, the effect of statins on chronic kidney disease (CKD) progression remains controversial
Introduction
Rosuvastatin is a prescription medication used to treat high cholesterol and prevent heart disease
Intended for U
Before taking Crestor, tell your doctor if you have ever had liver or kidney disease, diabetes, or a thyroid disorder, if you are of Chinese descent, or if you drink more than 2 alcoholic beverages daily
Crawford, As you are aware, on March 4th of this year, we petitioned the FDA to ban the recently-marketed cholesterol-lowering drug rosuvastatin (Crestor/AstraZeneca) because of seven post-marketing cases of life-threatening rhabdomyolysis and nine cases
Active liver disease, including unexplained, persistent elevations of hepatic aminotransferases
Recommended Dosage in Patients with Renal Impairment In patients with severe renal impairment (CLcr less than 30 mL/min/1
reports in less than one year since the drug was first marketed in this country – is approximately 75 times higher than the rate for all other statin
We reported the initial rosuvastatin dose across eGFR categories and evaluated for a dose effect on hematuria and proteinuria
g
Reported rates of renal failure were low compared with those found in epidemiologic studies in defined geographic populations, and have been
developed acute renal failure using a dose of only 10 milligrams a day and another patient in the U