The preliminary in vitro studies on viral infection models showed potential antiviral activities of type I and III interferons (IFNs), chloroquine
In this review, we explore how azithromycin may cytopathologically interface with local SARS-CoV-2 infection whilst exerting global immunomodulatory
Macrophages are important in innate and
Conclusions and implications: Azithromycin modulated classical activation of human monocytes by inhibition of TLR4-mediated signalling and possible effects on lysosomal
Adding budesonide did not reduce interferon-inducing effects of
Acyclovir is an anti-herpesvirus drug for use in people but Azithromycin (10 mg/kg, PO, q 24-72 hr) or fluoroquinolones can be used for cats with chronic disease
Azithromycin may reduce
Noteworthy, only azithromycin which is a synthetic derivative of erythromycin; the prototype of macrolides antibiotics first isolated from the soil bacterium Streptomyces erythraeus, but not erythromycin or telithromycin, has been shown to significantly increase rhinovirus 1B- and rhinovirus 16-induced interferons and
Azithromycin is a commonly prescribed antibiotic that belongs to the class of macrolide antibiotics
Noteworthy, only azithromycin which is a synthetic derivative of erythromycin; the prototype of macrolides antibiotics first isolated from the soil bacterium Streptomyces erythraeus, but not erythromycin or telithromycin, has been shown to significantly increase rhinovirus 1B- and rhinovirus 16-induced interferons and interferon-stimulated gene Azithromycin (AZM) is the first macrolide antibiotic in the azalide group, which inhibits the synthesis of bacterial To K
Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial
These mechanisms are universally involved in the innate response against infectious agents, and potentially against SARS-CoV-2
4–10 μM azithromycin in combination with the virus achieved the highest interferon-stimulating effect
Background: Rhinovirus infection is a major cause of difficult-to-treat asthma exacerbations
7 cells Azithromycin inhibits HEV replication and viral protein expression in multiple cell culture models with genotype 1 and 3 strains
December 2019 Volume 63 Issue 12 e00394-19 aac