The chemical name is: (R)- (-)- N ,α-Dimethyl- N-2 -propynylphenethylamine hydrochloride
See more This list may not describe all possible interactions
The transdermal patch of selegiline is available in strengths of 6 mg/24 h, 9 mg/24 h, and 12 mg/24 h, with each box
For transdermal dosage form (skin patch): Adults—At first, one 6-milligram (mg) patch once a day
Do not apply more patches or apply patches more often than prescribed by your doctor
increased tremors or uncontrolled muscle movements; worsening side effects of your other medications; high levels of serotonin in the body (when taken
Use transdermal selegiline exactly as directed
For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute
Emsam (selegiline transdermal) is used to treat major depressive disorder in adults
(-)-selegiline is a selegiline and a terminal acetylenic compound
You may report side effects to FDA at 1-800-FDA-1088
Dietary modifications are recommended in patients taking either selegiline transdermal 9 mg/24 hours or 12 mg/24 hours patches; tyramine-rich foods and beverages should be avoided beginning on the first day of the 9 mg/24 hours or 12 mg/24 hours patch and for 2 weeks after either a dose reduction to 6 mg/24 hours or following
These side effects include: vomiting, diarrhea, appetite loss, itchy skin, tremors, drooling, listlessness, disorientation, diminished hearing, or restlessness
Before Using
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur
The occurrence of stupor, muscular rigidity, severe agitation, and elevated temperature has been reported in some patients receiving the combination of selegiline and meperidine
Selegiline (the drug substance of EMSAM) is an irreversible inhibitor of monoamine oxidase (MAO), a ubiquitous intracellular enzyme
Typical Treatment Regimen: 5 mg twice daily with breakfast and lunch
5 to 2
Excretion Approximately 10% and 2% of a radiolabeled dose applied dermally, as a DMSO solution, was Dermal adhesion of EMSAM was examined after application of 6 mg/24 hours selegiline patches for 10 days to the upper torso
Apply the patch to a dry, smooth, intact skin area on your upper chest or back (below the neck and above the waist), upper thigh, or to the outer surface of the upper arm
This product is available in the following dosage forms: Patch, Extended Release