Benzilic acid rearrangement by 1,2-phenyl migrations afforded the pure product of 5,5-Diphenylhyantoin (Phenytoin) in a low percent yield (25%)
ooo④ dilantin : 252
The percent yield is determined by calculating the ratio of actual yield/theoretical yield
Percentage yield for synthesis of Benzoin was 43
To calculate the theoretical yield, we need to know the balanced chemical equation for the reaction that produced
Salem Five
Second, the overall final product yield is the product of each individual percentage yield
The reaction is proceeding via intramolecular cyclization to form
(Phenytoin sodium; e
8% and for formation of Dilantin from Benzil it was a decent 71
Benzilic acid rearrangement by 1,2
MgCO 3 → MgO + CO 2
In the same way, using N-cyanoguanidine, we obtained the corresponding phenytoin bioisoster (9) ( Table 2) in good yield (82%)
Percentage yield for synthesis of Benzoin was 43
Annual Percentage Yield - APY: The annual percentage yield (APY) is the effective annual rate of return taking into account the effect of compounding interest
Step 2 Oxidation of benzoin to benzil
To calculate the percent yield, we take the actual yield and divide it by the theoretical yield and multiply by 100 (Equation 6
Molecular weight of benzilic acid = 210 g/mole
278 grams of Dilantin and 0
For these calculations, use purified yield from step 1, crude yield from step 2 and purified yield for step 3
The first step can be advantageously performed using microwave activation
Phenytoin sodium was soluble in water (1 g/61 ml) and ethanol (1 g/12
Percent Yield is defined as the actual yield divided by the theoretical yield times 100
1) Percent Yield = ( Actual Yield Theoretical Yield) × 100 %
23gm/M Molecular weight of phenytoin= 252
01 and the actual Please set up a balanced equation of Dilantin from benzil
red or swollen gums, mouth sores; easy bruising, unusual bleeding, purple or red spots under your skin; or
At urea:benzil:KOH ratio of 1
Percentage Yield Solved Problem
The recommended starting dosage for pediatric patients is 5 mg/kg/day by mouth in two or three equally divided doses, with subsequent dosage individualized to a maximum of 300 mg daily in divided doses