Monitor: CBC count qWeek
3
9
Administer orally or by IV infusion
Drug class: Oxazolidinone antibiotics
Monitoring
The use of linezolid, an oxazolidinone antibiotic, in intensive care is such an example
Linezolid is an oxazolidinone-class antibacterial indicated in adults and children for the treatment of the following infections caused by susceptible Gram-positive bacteria:
A total of 1,837 patients who had received linezolid treatment from 1 January 2011 to 1 January 2021 were collected, 1,273
Linezolid Tablet for oral administration contains 600 mg linezolid as a film-coated compressed tablet
Food and Drug Administration (FDA) approved linezolid on 18 April 2000
Peripheral and Optic Neuropathy Advise patients to inform their physician if they experience changes in
Food and Drug Administration (FDA) in 2000 and entered the Chinese market in 2007 for clinical use (1, 2)
40
Co-administration of rifampin with linezolid resulted in a 21% decrease in linezolid C max [90% CI, 15% to 27%] and a 32% decrease in linezolid AUC 0 to12 [90% CI, 27% to 37%]
In a study by Zhidan Sun et al
It have been proved that continuous administration of linezolid might be critical for maximizing the
3
However, this medicine will not work for colds, flu, or other ZYVOX Tablets for oral administration contain 400 mg or 600 mg linezolid as film-coated
ZYVOX Tablet for oral administration contains 600 mg linezolid as a film-coated compressed tablet
‡ Oral dosing using either ZYVOX Tablets or ZYVOX for Oral Suspension [see How Supplied/Storage and Handling (16)]
Injection is supplied in single-use, ready-to-use infusion bags
This
Drugs such as warfarin and phenytoin, which are CYP2C9 substrates, may be given with linezolid without changes in dosage regimen
q12h infused over 1 h) was sampled at 1 h (peak or C max) and 12 h after linezolid dose administration (trough or C min) on two occasions (past data in red color)
The elimination half-life of linezolid is 5-7 hours, and twice-daily administration of 400-600 mg provides steady-state concentrations in the therapeutic range